A CYTOLOGICAL AND HISTOPATHOLOGICAL CORRELATIVE STUDY ON NEOPLASTIC LESIONS WITH MILAN SYSTEM FOR REPORTING SALIVARY GLAND CYTOPATHOLOGY.

Abstract

Salivary gland tumors are rare. Nevertheless, theaccurate preoperative diagnosis of themalignant potential of thelesion is essential for appropriate patient management. Therecently published Milan system for reporting salivary gland cytology (MSRSGC) is an effort to provide better communication regarding thenature of lesions to clinicians.Aim: To evaluate thediagnostic utility of fine-needle aspiration cytology (FNAC) of neoplastic salivary gland lesions and theMSRSGC applicability in risk stratification. This was a retrospective study of thecytological and histopathological correlation between neoplastic lesions of salivary gland lesions conducted over four years (August 2010- September 2014) in two tertiary care hospitals. There were 66cases of FNAC of salivary gland neoplasms. Thesensitivity, specificity, positive predictive value, negative predictive value, and overall diagnostic accuracy of FNAC were analyzed. Therisk of malignancy for MSRSGC was calculated. Theoverall diagnostic accuracy, sensitivity, specificity, and positive and negative predictive values were 93.94; 95.5; 99.8; 96.8, and 98.7%, respectively. By correlating thecytological diagnosis of benign neoplasm with histopathological diagnosis, therisk of malignancy was 0% and risk of neoplasm was 100%. For cases in thecategory suspicious of malignancy, risk of neoplasm was 100% and risk of malignancy was 85%. Thepresent study demonstrated that this salivary gland cytology reporting system was useful in classifying thelesions in well-delineated categories with ease. MSRSGC system of standardized reporting is helpful for guiding clinicians in appropriate management of thepatient. However, many multicenter studies with large sample sizes and long-term follow-up are needed along with wide propagation of its standardized reporting format to be adopted universally.