Abstract
The experimental setup to produce a cyclotron microbeam of 27 MeV α particles and 25 MeV protons is described. Using an ordinary doublet of quadrupole magnets with an aperture diameter of 2.5 in. as a focussing lens, a beam line with demagnification factors D CD = −3.3 and D DC = −16 was constructed. A beam spot with a diameter of less than 15 μm fwhm and an intensity of 0.06 nA was obtained for an extracted beam current of 300 nA. The experimental result is compared with the result of ray trace calculations. The microbeam of 27 MeV α particles is applied to the PIXE positional analysis of biomedical samples and that of 25 MeV protons is used to measure the density distributions in the samples based on the computed tomography (CT) principle. The experimental results of microPIXE and proton CT measurements on the eye from a mouse with a hereditary cataract are presented.
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