Abstract
Research in obese individuals without co-morbidities is a need of hour. In this study estimation of lipid peroxidation products (TBARS), Total anti-oxidant capacity(TAC), Ceruloplasmin and physical activity score was assessed in obese and non-obese healthy young adults of a urban population in South India with Correlation between the said parameters, and to know whether ceruloplasmin is an oxidant or an anti-oxidant. Study was conducted in 140 healthy young adults, categorised into obese and non-obese (male and female), with BMI > 28 and < 23 respectively. SQUASH questionnaire was filled by the participants to assess their physical activity status. WHR was measured followed by biochemical analysis of TBRS, TAC and ceruloplasmin by standard methods, after Blood pressure, glucose, TSH were found to be normal. Healthy obese and non-obese, aged 22–24 yrs, with BMI, WHR, TBRS, ceruloplasmin, physical activity score increased and TAC decreased, statistically in obese when compared to non-obese. (p<0.05) reflecting inflammatory, and oxidative stress changes. Positive correlation was found between WHR, ceruloplasmin and TBRS, proving ceruloplasmin to be an oxidant, than an antioxidant. Increased physical activity may be the reason for obese yet healthy individuals.
Published Version
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