A correlation study on depression and life events of patients with primary sjogren syndrome

Abstract

Objective To explore the relationship between life events and depression of patients with primary sjgren's syndrome(PSS). Methods 80 patients with PSS complicating depressive disorder were tested by self-rating depression scale(SDS) and life event scale(LES), and compared with the control group including 80 PSS patients with non-depressive disorder matched with age and sex.Then the correlation between SDS and LES were analyzed. Results The total score of life events(32.72±13.93), the score of negative life events(24.36±11.24), the score of SDS(58.60±16.78) and the frequency of life events(91.3%) in the research group were higher than those in control group(P<0.05), but the positive life events score(7.15±5.84) was lower than that in control group(9.76±7.29), and there was statistically significant difference between the two groups (P<0.05), there were more negative life events, especially on the aspects of family, work and study in the research group.There was positive correlation among the negative life events score, total score of life events and SDS score in the research group(P<0.01), meanwhile, negative correlation was revealed between the score of positive life events and SDS score in the research group(P<0.05). Conclusion Patients with PSS complicating depressive disorder experienced more negative life events which play an important role in depression of patients with PSS. Key words: Primary sjgren’s syndrome; Depressive disorder; Life events