Abstract

In many regions of the world, early diagnosis of non-small cell lung cancer (NSCLC) is a major challenge due to the large population and lack of medical resources, which is difficult toeffectively address via limited physician manpower alone. Therefore, we developed a convolutional neural network (CNN)-based assisted diagnosis and decision-making intelligent medical system with sensors. This system analyzes NSCLC patients’ medical records using sensors to assist staging a diagnosis and provides recommended treatment plans to physicians. To address the problem of unbalanced case samples across pathological stages, we used transfer learning and dynamic sampling techniques to reconstruct and iteratively train the model to improve the accuracy of the prediction system. In this paper, all data for training and testing the system were obtained from the medical records of 2,789,675 patients with NSCLC, which were recorded in three hospitals in China over a five-year period. When the number of case samples reached 8000, the system achieved an accuracy rate of 0.84, which is already close to that of the doctors (accuracy: 0.86). The experimental results proved that the system can quickly and accurately analyze patient data and provide decision information support for physicians.

Highlights

  • Lung cancer is the second most common type of cancer in the world (11.4%) after female breast cancer (11.7%) and remains the leading cause of cancer-related deaths [1].Based on the different histopathological characteristics of the tumor, lung cancer is classified into two main types: non-small cell lung cancer (NSCLC) and small cell lung cancer

  • The results show that our proposed new intelligent medical system can approach the diagnostic accuracy of NSCLC staging to the level of real doctors with good performance

  • The experimental results show that the intelligent medical system we built to assist diagnosis and decision-making can provide doctors with fast and accurate decision-making suggestions, effectively simplify the diagnosis process, saving time, and reducing the load of tedious medical work for doctors

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Summary

A Convolutional Neural Network-Based Intelligent Medical

System with Sensors for Assistive Diagnosis and Decision-Making in Non-Small Cell Lung Cancer. Xiangbing Zhan 1 , Huiyun Long 1, *, Fangfang Gou 2 , Xun Duan 1 , Guangqian Kong 1 and Jia Wu 2,3, *. Research Center for Artificial Intelligence, Monash University, Clayton, VIC 3800, Australia

Introduction
Related Work
Overall System Framework
NSCLC Staging Prediction Model
The Skip-Gram
CNNOperation
Prediction
Diagnostic Data Parameters
Auxiliary
Evaluate
Decision-Making and Discussion
Conclusions
Findings
Methods
Full Text
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