Abstract
Mangiferin always draws the attention of traditional as well as modern medicinal chemists because of its ease of chemical derivatization and diverse biological activities, including anticancer, anti-inflammatory, neuroprotective, antidiabetic, analgesic, antimalarial, anticonvulsant, laxative, cardiotonic, hemopoietic, antioxidant, antimicrobial, antipsychotic, anticoagulant, and antihypertensive properties. This review focuses on a detailed and updated overview of the synthesis of mangiferin derivatives and their diverse biological activities, with examples from both patented and non-patented literature.
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