Abstract
As a comprehensive review of cancer, oncogenes, and CRISPR, this review explores the transformative potential of CRISPR technology in combating cancer, particularly focusing on lung cancer and oncogenes. CRISPR’s precision gene-editing capabilities offer a promising avenue for developing more targeted cancer therapies, overcoming the limitations of current treatments such as chemotherapy and radiation, which often fail due to cancer cell heterogeneity and resistance. Additionally, this review proposes the potential use of CRISPR to target specific oncogenes like EGFR and its significant promise for improving treatment outcomes in lung cancer by directly modifying or regulating gene function. This review synthesizes current research, highlighting the integration of CRISPR with other therapeutic modalities to enhance the effectiveness of cancer treatments, delivery systems that improve targeting and minimize off-target effects, and the future directions in CRISPR-mediated lung cancer therapy.
Published Version
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