A comprehensive overview on phytomedicines as an upcoming/emerging candidate for the management of epilepsy

Abstract

Background: The word "epilepsy" refers to a category of chronic CNS illnesses characterised by spontaneous occurrence of seizures, which are typically accompanied by loss of consciousness and uncontrollable shaking of the body (convulsions). Epilepsy is one of the most commonly occurring non-communicable neurological disorder that affects people of all age groups. By preventing discharge and inducing hypnosis, anticonvulsant medications are used to manage convulsions. The medication used for the therapy includes phenytoin (PHT), diazepam, valproate (VPA), levetiracetam, etc. These medications have brand-new effectiveness ranges and brand-new side effects. They also represent a significant cost increase. Herbal medicine, which has its roots in ancient civilizations, involves the use of medicinal plants to treat diseases and promote overall well-being. Although the widespread use of herbal medicine as an antiepileptic, there is little solid data supporting the effectiveness and safety of the majority of herbs. Additionally, the herbal remedy needs to pass a rigorous, evidence-based review. As herbal drugs are derived from natural sources, they are often considered safer than synthetic drugs. Therefore, there is a growing interest in exploring the potential of herbal medicine for treating neurodegenerative diseases such as Parkinson's disease. Due to their lower adverse effects, herbal medications are becoming more and more popular for the adjuvant treatment of epilepsy.
 Objective: The objective of this article is to investigate whether herbal medications have potential as a treatment option for Parkinsonism, and to provide a clear understanding of the current state of research on this topic.
 Keywords: Convulsion, epilepsy, herbal treatment, seizures, phytoconstituents, herbal medicine, GABA.