A comparison of swallow-related submandibular contraction amplitude and duration in people with Parkinson’s disease and healthy controls

Abstract

Purpose To compare the contraction amplitude and contraction duration of submandibular muscles during the pharyngeal stage of swallowing in people with Parkinson’s disease (PD) compared to normal controls. Method A prospective cross-sectional study design was utilised to recruit 24 participants from the regional area. A total of 14 people with PD and 10 healthy controls (HC) were recruited. Participants swallowed three volumes of thin liquid (5mL, 10mL, 15mL) while the activity of the submandibular muscles was recorded using surface electromyography. Measurements of contraction amplitude ratio (normalised to a maximum voluntary contraction) and contraction duration were computed from recorded electromyographic signals. Receiver Operating Characteristics (ROC) were computed for variables associated with significant main effects. Result Analyses revealed a significant effect of group on contraction amplitude ratio but not contraction duration. There were no significant effects of bolus volume on the dependent variables. ROC analysis indicated that contraction amplitude ratio accurately predicted group assignment in 77% cases. Conclusion Findings revealed that a majority of people with PD in this study utilised a greater percentage of their maximum contraction force in submandibular muscles when swallowing compared to normal controls. Further research is needed to determine if this inefficiency is consistent across larger samples and whether it is due to elevated baseline muscle activity, a compensatory behaviour to accomplish a more effective swallow, or both.