A comparison of preoperative soft tissue contour versus bone accuracy as a predictor of quality of life outcomes in osseous free flap jaw reconstruction using occlusal-based virtual surgical planning

Abstract

ObjectivesOcclusal based virtual surgical planning (VSP) prioritises placement of endosseous dental implants, over replicating native bone contour. This may compromise facial aesthetics. This study aims to compare function and health-related quality of life (HRQOL) following maxillomandibular reconstruction according to ability to replicate preoperative soft-tissue contour and virtual plan. Materials and methodsPatients who had undergone occlusal based VSP osseous free flap reconstruction of the maxilla or mandible, with high-resolution pre- and postoperative facial computerised tomography imaging, and completion of FACE-Q questionnaire were retrospectively identified. Accuracy of reconstruction compared to preoperative soft tissue contour and virtual plan, was measured using 3DSlicer® and CloudCompare® in three dimensions. Random effects modelling determined associations between bony and soft tissue accuracy and HRQOL/functional domains. ResultsTwenty-two patients met the inclusion criteria. For mandibular and maxillary reconstructions, better soft tissue accuracy was associated with improved appearance (p = 0.048) and appearance distress (p = 0.034). For mandibular reconstructions, better soft tissue accuracy was associated with improved smile (p=0.039) and smile distress (p=0.031). For maxillary reconstructions, better bony accuracy was associated with improved appearance (p=0.023) and drooling distress (p=0.001). Unexpectedly, better bony accuracy was associated with worse eating and drinking (p=0.015), oral competence (p=0.005) and eating distress (p=0.013) in mandibular reconstructions. ConclusionWhilst soft tissue accuracy was associated with better functional and HRQOL outcomes, bone accuracy was associated with worse oral function/distress in mandibular reconstruction. These results need validation but should be considered when performing occlusal-based VSP, which prioritises dental rehabilitation over replicating facial bony contour.