Abstract

IN 1928 STRICKER AND GRUTER (1) showed that the injection of anterior pituitary extracts stimulated abundant milk secretion in the rabbit at the end of pseudopregnancy. Since that time numerous investigators have reported that milk secretion can be initiated in laboratory mammals by the injection of various exacts of the pituitary (for review see Turner, 1). For the assay of galactin Gardner and Turner (3) suggested a method based upon the induction of increasing degrees of lactation in pseudopregnant rabbits from mere duct lactation (+), to the type of lactation observed in parturient animals (+ + + +). Riddle and Baucher (4) first showed that pituitary preparations were capable of producing proliferation of the pigeon crop gland. Following this discovery several methods of assay based upon pigeon and dove crop gland responses have been described (see Riddle and Bates, 5, for review).

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