Abstract

The blood glucose level of people with diabetes can be normalized through an appropriate diet, physical activity, the use of chemical drugs and medicinal plants. This study aims to investigate the effects of low-calorie diets (1200, 1500, and 1800 kcal) on glucose and serum lipids in poorly controlled type 2 diabetic patients. This clinical trial was conducted among 60 patients with type 2 diabetes mellitus. The criteria for entering the study were fasting blood glucose higher than 130 mg/dl, hemoglobin A1C higher than 7% and BMI higher than 25. Blood glucose, fasting blood glucose and lipid levels were measured before and after intervention two hours after each meal. Patients were trained by an expert. Then, the questionnaires were completed and analyzed. In this study, the mean fasting blood glucose level in patients who used 1500 and 1200 kcal diet decreased significantly after intervention (p<0.05). Glucose decreased significantly after two hours using a 1500 kcal diet (p<0.009). In addition, triglyceride and cholesterol levels were significantly reduced in patients who used the 1500 kcal diet (p<0.05). Although, there was no significant difference in blood glucose levels between 1200, 1500 and 1800 kcal diets based on gender, residencency and BMI. Regarding the fact that there was no significant difference in reducing blood glucose and serum lipids between 1200 and 1500 kcal diets. It is recommended to use a 1500 kcal diet instead of 1200 kcal diet, which imposes fewer limitations and is easier to tolerate.

Highlights

  • Diabetes mellitus is one of the most common endocrine abnormalities and one of the biggest health problems in urban communities(Gyawali, Ferrario, Van Teijlingen, & Kallestrup, 2016; Joshi, Malla, Bhattarai, & Shrestha, 2017; Veghari et al, 2010)

  • This study was conducted among 50 patients with poorly control type 2 diabetes; 21 patients (42%) had 1200 kcal diet, 15 patients (30%) had 1500 kcal diet and 14 patients (28%) had 1800 kcal diet

  • The of 1500 kcal diet resulted in a significant decrease in fasting blood glucose and blood glucose taken two hours after meals in the subjects

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Summary

Introduction

Diabetes mellitus is one of the most common endocrine abnormalities and one of the biggest health problems in urban communities(Gyawali, Ferrario, Van Teijlingen, & Kallestrup, 2016; Joshi, Malla, Bhattarai, & Shrestha, 2017; Veghari et al, 2010). The International Diabetes Federation estimates the number of people involved with this disease to be more than 400 million people, i.e. about 6% of the adult population(Organization, 2017) For controlling this disease, nutritional care is primarily important and other treatment efforts alone will not be enough without considering advice and nutritional care. Given that most type 2 diabetic patients do not have enough knowledge about their diet, appropriate nutritional education will play an important role in controlling their disease(Shah, Kamdar, & Shah, 2009). It is often controlled by dietary and lifestyle changes, but oral hypoglycemic or insulin drugs may be necessary(Asif, 2014). Hyperglycemia can be reduced in obese people by reducing about 5-10 kg of body weight (Wilding, 2014)

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