A comparative Study of Two Techniques for Repairing of Tracheal Defect in Dogs.

O H Al-Hyani

doi:10.30539/iraqijvm.v43i1.462

Abstract

The objective of this study was designed to evaluate the possibility of repairing tracheal cartilage defect in dogs. 18 local breed dogs of both sexes was used in this study, they are allocated into 2 equal groups. A tracheal defect was induced in the cervical part of the trachea as a window about 3cm x 2cm in diameter. The defect was closed in 1st group by using polypropylene mesh and bone cement substance, while in 2nd group polypropylene mesh with fresh auto- bone marrow. Post-operative study including, clinical observation, gross pathology and histopathological evaluation was performed in all animals. The most important postoperative clinical observation was represented by subcutaneous emphysema at the site of operation in the 2nd group animals, which gradually disappeared within few days. Otherwise no other important complications was reported in both groups during the period of the experiment. The gross pathological changes and biopsy collection for all animals was done at 15, 30, 60 postoperative days. The gross examination revealed complete closing of the induced tracheal defect in all operated animals and a mild adhesion with the surrounding tissues. In both groups, the histopathological features was represented by newly granulation tissue formation and areas of hyaline cartilage degeneration and necrosis. The cartilage regeneration was showed only in 2nd group through by formation of new cartilage cells. In conclusion, it can use both techniques for reconstruction of tracheal defect in dogs but the auto bone marrow group was regarded the best due to improvement of the healing process. .

Highlights

Tracheal restoration is one of the biggest reactions but still be incorporated by the challenges and sophisticated thoracic surgery surrounding tissue [6]
Number types of synthetic or natural subjects were used to repair tracheal defects such as muscle flap, mesh patch fashioned from a nickel-titanium, Marlex mesh and prosthesis framework made from high-porous synthetic material lined with autogenous mucosa and biodegradable glues such as gelatin are used to improve an airtight attachment between host tissue and the prosthesis [12,13,14]
(19).The aim of this study was to evaluate the ability of polypropylene mesh with bone cement or with fresh auto-transplantation of bone marrow to repair tracheal defect in dogs

Summary

Introduction

Tracheal restoration is one of the biggest reactions but still be incorporated by the challenges and sophisticated thoracic surgery surrounding tissue [6]. The perfect use of prosthetic materials, tissue flaps, stents, synthetic materials (tracheal prosthesis) used auto grafts, or a mixture of these methods have for tracheal defect should be sealed, sufficient been reported, but complications associated constancy, and well tolerated by the host. It with these methods including migration, should cause minimal inflammatory dislodgement, material degradation failure, chronic bacterial infection, obstruction because of granulation tissue formation, stenosis, necrosis, anastomosis failure, long duration immunosuppression, lack of suitable donor source, decrease of adequate vascularization, and epithelium [11]. A number types of synthetic or natural subjects were used to repair tracheal defects such as muscle flap, mesh patch fashioned from a nickel-titanium, Marlex mesh and prosthesis framework made from high-porous synthetic material lined with autogenous mucosa and biodegradable glues such as gelatin are used to improve an airtight attachment between host tissue and the prosthesis [12,13,14]

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Conclusion