Abstract
The 5' flanking region (1.2 kb) and the first exon and intron (1.5 kb) of the human αS1-casein (CSN1) gene, and the 5' flanking sequence (2.0 kb) of the human β-casein (CSN2) gene were cloned and sequenced. Strong sequence homology was observed between the 5' flanking regions of the casein genes of humans and other mammals. Several transcriptional regulatory elements (GRE, C/EBP, YY1, STAT5) identified in the rat β-casein gene were conserved in both human casein genes.
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