Abstract
This article reports the fabrication, microstructural analysis, mechanical and biological properties of scaffolds synthesized from composites containing 20 At. % Ca10(PO4)6(OH)2 (HAP) and 80 At. % SrTiO3 (ST) (20H-80S), and 20 At. % Ca10(PO4)6(OH)2 and 80 At.% Ba0.5Sr0.5TiO3 (BST) (20H-80B). The microstructural analysis reveals the presence of reflections from both the monoliths along with smaller sized grain in 20H-80S (92.2 ± 4.5 nm). This resulted in improved mechanical strength compared to 20H-80B, which has a higher grain size (110.3 ± 5.1 nm) and higher porosity along with the biomineralization capacity of 20H-80B (Ca/P-1.64) which is found higher compared to 20H-80S (Ca/P-1.52). The higher porosity also reflected in high protein adsorption on 20H-80B. The scaffolds' cytocompatibility revealed the cell viability >90%, rendering the scaffolds suitable for bone tissue engineering applications.
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