Abstract
The aim of this study was to systematically investigate the apatite layer formation and protein adsorption on the bioceramics, trying to reveal their relationship and the mechanisms of the process. Four different materials, hydroxyapatite (HA), apatite/wollastonite bioactive glass ceramics (BGC), biphasic calcium phosphate (BCP), and nano-hydroxyapatite (nHA), were prepared to meet the specific tissue engineering scaffold requirements. The porous samples in four groups were immersed into simulated body fluid (SBF) solution, and the structural and morphological changes for different times (maximum of 14 days) were analyzed. Then, the effect of their structure and chemical composition on protein adsorption capacity was systematically compared.
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