Abstract
The aim of this study was a comparative statistical analysis of three categories of maxillary odontogenic cysts, evaluating frequency in relation to localization (mandibular or maxillary region), age and gender of patients. The study was a retrospective cohort study conducted at the University Hospital of Messina. Three hundred and fifty-six maxillary odontogenic cysts were classified into 283 inflammatory, 43 developmental and 30 neoplastic cysts. Female patients are more affected by developmental odontogenic cysts, while male patients are more affected by inflammatory odontogenic cysts. Both the mandibular and maxillary regions were affected mainly by inflammatory odontogenic cysts; no significantly statistic relationship was found between lesions and age. A significant association between odontogenic cyst lesions and patient gender was found. No significant association between histological features of lesion and age of patient was observed, nor subtype of odontogenic disease and localization (mandibular or maxillary).
Highlights
IntroductionIrrespectively of regional distribution (mandibular or maxillary), represent the most frequent bone cysts and by definition are lined by epithelium
Maxillary cysts, irrespectively of regional distribution, represent the most frequent bone cysts and by definition are lined by epithelium
The mandibular region was affected in 60.5% of cases and the maxillary region in 39.5%
Summary
Irrespectively of regional distribution (mandibular or maxillary), represent the most frequent bone cysts and by definition are lined by epithelium. According to the different origin of epithelial lining, they are classified into two-main groups: odontogenic and non-odontogenic cysts; cystic spaces without epithelial lining represent pseudocysts [1,2,3,4,5]. This subdivision is supported by studies on the distribution of cytokeratins in the epithelial lining. Cytokeratins are cytoplasmic strands, represented by at least 19 different polypeptides, which represent the main structural proteins of all epithelial cells It appears that all structures deriving from odontogenic epithelium have a superimposable cytokeratine content [6]. According to the 4th edition of the WHO classification, odontogenic cysts can be classified
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