A Comparative Pharmaceutical Study of Abhrasindoora by Traditional and Contemporary Method

Abstract

Background: Rasashastra is a Pharmacotherapeutics of Mercurial, Metallic, and Mineral preparations Abhrasindoora (AS) is a unique Herbo-Metallic-Mineral Compound, which is mainly indicated in respiratory diseases. Method: AS contains Dhanyabhraka (Bio-purified Black Mica Powder), Shodhita Parada (Bio-purified Mercury), and Shodhita Gandhaka (Bio-purified Sulphur) in equal proportion. These mixtures were subjected to trituration in Kharal till Kajjali formation (ABS-72 hrs) followed by impregnation of latex of Arka (Calotropis procera linn) (QS) (16 hrs) and Vatashunga (Ficus benghalensis linn) (QS) (15 hrs). Then Batch-A & Batch-B were prepared separately in Valuka Yantra and Electric Muffle furnace by maintaining mild (150 0C-250 0C), (150 0C - 300 0C) moderate (250 0C -400 0C), (300 0C -450 0C) and intense temperature (400 0C - 550 0C), (450 0C -650 0C) respectively. Observation: Batch A AS was prepared in 37 hours and the total yield of the product obtained was 54 grams. Batch B AS was prepared in 21 hours and the total yield of the product obtained was 25 grams. Jet black colour Kajjali of AS turned to dark red which was sublimated at the neck of Kachkupi. Conclusion: The yield of Batch A was more than Batch B but it took more time. Hence, the preparation of Kupipakva Rasayana in a sand bath should be done repeatedly to conclude it is a more economic and convenient process.