Abstract
Chronic Kidney Disease itself indicates chronicity with irreversible damage to the kidneys due to main leading factor in many cases nowadays as a major cause which is Hypertension and Diabetes mellitus type 2, which clinically presents as symptomless sometimes in initial stages and further presents with pedal oedema, decreased appetite, nausea, difficulty in micturition/decreased urine output, frothy/foamy urine, fatigue. Usually it is manifested through various lab investigations such as kidney function test in which increase in serum urea levels, serum creatinine and other are seen i.e., a waste product made by our muscles, also Kidney’s one of the vital function is production of erythropoietin.Ayurveda has played an essential role in the early stages of renal failure in the hunt for this effective and safe treatment. Mutra is a kleda product, according to Ayurveda. Acharya Sushruta, a worldrenowned surgeon, has a good description of Mutrapravrutti.Creatine and Creatinine are not the same substances. Creatine from liver transported to other tissues. Creatine are 98% present in skeletol and heart muscles.in these muscles it gets converted to high energy source creatine phosphate. In skeletol muscle approximately 1/4th of Creatine exists as free Creatine and 3/4th exists as Creatine phosphate compound. It acts as a storage form of energy in the muscle. The amount of C. phosphate in the body is proportional to the muscle mass
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