A clinical study of trabeculectomy combined with scleral tunnel drainage and MMC for refractory glaucoma

Abstract

Objective To explore the clinical effect of treatment for refractory glaucoma of trabeculectomy combined with scleral tunnel drainage and mitomycin C.Methods A total of 103 patients (108 eyes) with refractory glaucoma Were divided into two teams randomly,51 patients (53 eyes) were treated with trabeculectomy combined with scleral tunnel drainage and mitomycin C,52 patients (55 eyes) were treated with trabeculectomy combined with mitomycin C.Visual acuity,intraocular pressure,filtered bleb formation,successful rate and complication Were compared postoperatively between the two teams.The follow-up period was l to 24 months postoperatively.Results There was no significant difference in visual acuity between two teams at l month post operation (P>0.05).There was significant difference between two teams in sense of light at 12 months post operation(P<0.05),in intraocular pressure (P<0.05) and formation rate of function-al filtered blebs (P<0.05) at every period and in successful rate at 12 and 24 months post operation (P< 0.05).Conclusions Trabeculectomy combined with scleral tunnel drainage and mitomycin C is a kind of operation ideally for refiactory glaucoma because of its easy application,reliable and stable effect and successful rate. Key words: Trabeculectomy; Scleral tunnel; Mitomycin; Refractory glaucoma .