Abstract
Presented are three clinical observations of patients with a rare, but one of the oldest, genetic disease, which according to modern concepts belongs to the group of autoinflammatory diseases — familial Mediterranean fever. In the cases described, the diagnosis was first made in adulthood. The main purpose of the description of these cases is to draw the attention of practitioners to the possibility of early diagnosis and adequate pathogenetic therapy of this cohort of patients with an ethnic predisposition, but manifested regardless of the place of modern residence.
Highlights
Hereditary spherocytosis (NS) is hereditary hemolytic anemia due to a defect in the erythrocyte membrane, leading to a characteristic change in the shape of erythrocytes, which is heterogeneous in terms of the severity of clinical manifestations, defects in membrane proteins and the type of inheritance
The clinical course of NS varies in severity from asymptomatic to severe with massive hemolysis
An important role belongs to the knowledge of the family history and a comprehensive examination, which makes it possible to exclude other causes of hemolysis
Summary
Hereditary spherocytosis (NS) is hereditary hemolytic anemia due to a defect in the erythrocyte membrane, leading to a characteristic change in the shape of erythrocytes (spherocytes), which is heterogeneous in terms of the severity of clinical manifestations, defects in membrane proteins and the type of inheritance. A clinical observation of hereditary spherocytosis in an elderly patient For citation: Burtseva E.A, Snezhko I.V., Nagornaya G.Yu., Shatokhin Yu.V. A clinical observation of hereditary spherocytosis in an elderly patient.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
