Abstract
Objective To investigate the error monitoring function damages on the patients with schizophrenia (SCH). Methods A total of 32 patients with schizophrenia were compared with matched 34 health controls (HC) on the error monitoring tasks which were compiled by E-Prime. Results The comparison between SCH group ((713.22±174.52)ms, ( 491.14±170.29) ms, ( 1060.31±130.84) ms, (8.28±12.55)time, ( 8.00±7.53)time respectively) and HC group ((560.73±156.94) ms, (395.62±188.03) ms, (989.85±104.33) ms, (2.97±4.13) times, (3.12±6.50) times) on the reaction time of choice, assessment, incongruent condition, the numbers of uncertain and the numbers of dropout were significant (t=-3.737, P=0.000; t=-2.159, P=0.035; t=-2.426, P=0.018; t=-2.282, P=0.022; t=-2.824, P=0.006). The SCH group and HC group did not significantly difference in Full Correct((124.72±23.74)/(131.74±21.96)times), Full Error((15.69±17.64)/(13.35±18.63)times), Part Correct((6.83±10.40)/(4.21±7.03)times), Part Error((2.91±10.91)/(0.62±1.10)times) and Accuracy((0.831±0.161)/(0.874±0.159))(P>0.05). There was no significantly correlation among the course of disease, HAMA, HAMD and the error monitoring. Conclusion These results demonstrate that the error monitoring function damages on the patient with SCH may be involved in the dysfunction of anterior cingulate cortex. Key words: Schizophrenia; Error monitoring; Anterior cingulate cortex
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call