Abstract
Sorbus commixta Hedl. (Rosaceae) has been traditionally used in oriental countries for the treatment of asthma and other bronchial disorders. In this study, a chalcone glycoside was isolated from the ethyl acetate extract of the fruits of this plant. The compound was identified as neosakuranin based on the spectroscopic analysis and comparion with literature data. This is the first report of isolation of neosakuranin from Sorbus commixta.
Highlights
Sorbus commixta Hedl. (Rosaceae) has been used for the treatment of cough, asthma, and other bronchial disorders in East Asian countries, including Korea, China and Japan [1,2,3,4,5]
This paper deals with the isolation of a chalcone glycoside from the fruits of S. commixta
The compound was identified by the assignment of the 1H- and 13C-nuclear magnetic resonance (NMR), heteronuclear multiple bond connectivity (HMBC), heteronuclear multiple quantum coherence (HMQC), correlated spectroscopy (COSY) together with mass spectrum (MS), infrared (IR), ultraviolet visible (UV-vis) spectra and comparison with the literature data [10,11,12]
Summary
Sorbus commixta Hedl. (Rosaceae) has been used for the treatment of cough, asthma, and other bronchial disorders in East Asian countries, including Korea, China and Japan [1,2,3,4,5]. This paper deals with the isolation of a chalcone glycoside from the fruits of S. commixta. Fractionation and purification of the methanol extract of S. commixta fruits using silica gel and Sephadex LH-20 column chromatography together with preparative high performance liquid chromatography (HPLC) led to the isolation of the chalcone glycoside 1.
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