A central giant cell granuloma in anterior mandible- A case report

Abstract

Central giant cell granuloma (CGCG) is an uncommon, benign but aggressive osteolytic neoplasm of the craniomaxillofacial region with an unknown etiology. The incidence in the general population is very low with age predilection generally younger than 30 years with a female predominance. CGCG is divided into rare aggressive variant and a common non aggressive variant based on clinicoradiographic features. It is usually unifocal and located at the anterior region of the mandible or maxilla, although are more frequently found in the mandible. A case of a large destructive CGCG involving the entire symphysis of mandible, causing extensive bony resorption, buccal and lingual cortical expansion in a female patient of age 32 years is presented.