Abstract
In the last decade, many studies highlighted the role of 3D printing technology in the fabrication of smart and programmable sensors for various biomedical-based 4D printing applications. But, hitherto, much less has been reported on the investigation of the antioxidant and drug-release capabilities of 3D printable polymer matrix for treating the cancerous cells of veterinary patients (mostly in the mouth of bovines and equines). This study reports the investigations performed on the drug-delivery efficiency of medicine-loaded polymer matrix for 3D/4D printing applications of user-driven drug-delivery systems as a cure for veterinary cancer patients. The pilot study performed on the drug-release efficiency and antioxidant properties of polyvinyl alcohol (PVA) polymer matrix loaded with ascorbic acid (as drug) may be considered as a framework to prepare a 3D printable (biocompatible polymer matrix) and 4D-capable user-driven drug to treat the cancer cells of veterinary patients with a defined and customizable approach of mouth-cancer treatment. The combination of 4D printing with smart materials offers a promising future in the medical field. In this regard, special emphasis is placed on the most recent advances in the innovation and development of stimuli-responsive materials, which are activated and respond over time to chemical, physical, and biological stimuli, and their use in the fabrication of 4D printing of smart parts such as intelligent tissue-engineered scaffolds, smart orthopedic implants, and targeted drug-delivery systems.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
