Abstract
Scrub typhus is one of the endemic diseases leading to acute febrile illness in the topical countries. It can present with its various manifestations ranging from asymptomatic illness to serious multiorgan dysfunctions. The most common pathophysiology behind this multisystem manifestation is the systemic vasculitis due to exaggerated immune response. Early diagnosis and aggressive treatment along with close monitoring of vitals with best supportive measures may be the satisfactory response to the physician. Here, in this case series we are discussing five cases of scrub typhus presented with various atypical and uncommon manifestation HLH (Case 1), Encephalopathy, Pancytopenia, AKI, Intrahepatic cholestasis, Pancreatitis (Case 2), meningoencephalitis (Case 3), myocarditis (Case 4) and Leukemoid reaction, ALF (Case 5).
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