Abstract
The Journal is the primary organ of Continuing Paediatric Medical Education in Sri Lanka. The journal also has a website. Free full text access is available for all readers.The Sri Lanka Journal of Child Health is now indexed in SciVerse Scopus (Source Record ID 19900193609), Index Medicus for South-East Asia Region (IMSEAR), CABI (Centre for Agriculture and Bioscience International Global Health Database), DOAJ and is available in Google, as well as Google Scholar.The policies of the journal are modelled on the Committee on Publication Ethics (COPE) Guidelines on Principles of Transparency and Best Practice in Scholarly Publishing. Sri Lanka Journal of Child Health is recognised by the International Committee of Medical Journal Editors (ICMJE) as a publication following the ICMJE Recommendations.
Highlights
Toxic shock syndrome (TSS) is an acute febrile illness with mucocutaneous manifestations and multisystem involvement, often associated with focal staphylococcal infection[1]
All 3 major criteria were present in this 8 year old girl viz. high fever, hypotension and rash
Several minor criteria were present viz. mucous membrane inflammation, diarrhoea, liver abnormalities and renal abnormalities. She had myocardial dysfunction which is not listed among the minor criteria
Summary
Toxic shock syndrome (TSS) is an acute febrile illness with mucocutaneous manifestations and multisystem involvement, often associated with focal staphylococcal infection[1]. Many cases occur in menstruating women who are 15-25 years of age and use tampons or other vaginal devices in the presence of vaginal colonisation or infection with toxinproducing strains of staphylococcus aureus[2]. TSS, occurs in children, non-menstruating women and men associated with wound infection, nasal packing, sinusitis, tracheitis, pneumonia, empyema, abscesses, burns, osteomyelitis and primary bacteraemia[3]. Staphylococcus aureus produces several superantigenic exotoxins such as toxic shock syndrome toxin-1 (TSST-1) and staphylococcal enterotoxins[5]. Overactivation of T cells by these exotoxins and resultant overproduction of cytokines are the primary causes of TSS6. Bacterial cultures of associated focus (e.g. vagina, abscess) before administration of antibiotics usually yield S. aureus, this is not a required element of the definition[8]
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