Abstract
BackgroundPropofol infusion syndrome (PRIS) is a rare but potentially lethal side effect during propofol administration.Case presentationThe patient was scheduled for abdominal aortic aneurysm resection and reconstruction. Propofol used during sedation for ventilation after the surgery-induced rhabdomyolysis, heart failure, and renal failure. Discontinuation of propofol administration led to a dramatic improvement in the fatal symptoms, resulting in a diagnosis of PRIS.ConclusionsWe herein report a rare case of a PRIS during sedation in the intensive care unit after abdominal aortic aneurysm surgery. Physicians using propofol should therefore be aware of the potential risk of PRIS.
Highlights
Propofol infusion syndrome (PRIS) is a rare but potentially lethal side effect during propofol administration
Propofol infusion syndrome (PRIS) is a rare but potentially lethal side effect of propofol, which is commonly used in anesthesia and in intensive care for sedation
It is characterize by symptoms such as metabolic acidosis, rhabdomyolysis, arrhythmia, renal failure, and myocardial failure
Summary
Propofol infusion syndrome (PRIS) is a rare but potentially lethal side effect of propofol, which is commonly used in anesthesia and in intensive care for sedation It is characterize by symptoms such as metabolic acidosis, rhabdomyolysis, arrhythmia, renal failure, and myocardial failure. Case presentation A 70-year-old female patient was scheduled for abdominal aortic aneurysm resection and reconstruction She had undergone general anesthesia for surgery of purulent cervical spondylitis about 6 years ago without any. From the day after the propofol infusion was stopped, the fever decreased to 36.8 °C, CPK started to decease, and the hemodynamics improved dramatically (Fig. 1). Two weeks later, her respiratory condition improved, and the ventilator was able to be removed. Ten months after the operation, the patient’s communication level had improved, but hemiplegia remained due to cerebral infarction and muscle weakness due to disuse, so she was transferred to a rehabilitation hospital for functional recovery
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