A Case of Recurrent Ovarian Granulosa Cell Tumor Associated with Sarcomatoid Change

Abstract

Granulosa cell tumors of the ovary are malignancies that originate from the sex-cord stromal cells of the ovary and represent 2% to 5% of all ovarian cancers. Slow growth with a tendency for late recurrence characterizes a natural history of this tumor. So this tumor needs a prolonged follow-up. As a result of recent literature in Korea, the findings are 3 cases of juvenile granulosa cell tumor and 1 case of adult granulosa cell tumor. Previous case of adult granulosa cell tumor was presented recurrence with hepatic metastasis after 9 months of first diagnosis and operation. We describe here a 52-year-old women with recurrent granulosa cell tumor after total abdominal hysterectomy with right salpingo-oophorectomy and left ovarian wedge resection because of right ovarian granulosa cell tumor 12 years ago. Our case presented late recurrence character of granulosa cell tumor. We report 1 case of recurrent adult type granulosa cell tumor associated sarcomatoid change with a brief review of literatures.