Abstract
Background: The role of trauma in the pathophysiology of malignant melanoma remains controversial. We report a case of malignant melanoma (epithelloid type) in which a characterized trauma seems implicated in tumour progression with a review of the literature.Patients and Methods:A 45-year-old male consulted for ulcerative lesion over right side of face. He had trauma at the age of 7 leaving a pigmented scar on which while shaving there was trauma followed by nonhealing ulcer. Physical examination revealed an ulcer 4x4 cm ulcer over right zygomato temporal region. Histological study showed an ulcerated superficial spreading melanoma. Wide excision and coverage done with local flap.Conclusion: Our observation and literature research provide convincing arguments for a role of trauma in the development of malignant melanoma epithelloid type. Dermatologists and Surgeons must pay attention to any unusual changes in an old scar.
Highlights
IntroductionThe number of cases of malignant melanoma worldwide is increasing faster than any other form of cancer amongst Caucasians[2]
Melanoma is a malignant tumour of melanocytes[1]
The most common site is the legs and melanomas in men are most common on the back[6]
Summary
The number of cases of malignant melanoma worldwide is increasing faster than any other form of cancer amongst Caucasians[2]. When compared to other forms of skin cancer, the disease is relatively uncommon[3]. It causes the majority (75%) of deaths related to skin cancer[4]. Melanoma is a life threatening but potentially treatable form of cancer if diagnosed and managed at an early stage. Guidelines have been published to assist healthcare workers in the recognition of malignant melanoma of the skin[5]. Doctors diagnose about 160,000 new cases of melanoma yearly. The most common site is the legs and melanomas in men are most common on the back[6].
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