Abstract
Mucormycosis is an invasive fungal infection, often acute and extremely severe, occurring in patients with an underlying condition. Coinfection in patients with coronavirus disease 2019 (COVID-19) has been reported, often bacterial. A 24-year-old female is presented with acute fatal rhino-orbital mucormycosis and COVID-19.We report one of the first cases of rhino-orbital mucormycosis and COVID-19. With this case, we highlight the importance of considering mycotic coinfection in COVID-19 patients with diabetes.
Highlights
Mucormycosis (Zygomycosis) is an invasive fungal infection, often acute and extremely severe caused by opportunist and ubiquitous fungi belonging to the class Phygomycetes, subclass Zygomycetes, order Mucorales, family Mucoraceae; usually by the following species: Absidia corymbifera, Apophysomyces elegans, Cunninghamella bertholletiae, Mucor rouxii, Rhizomucor pussillus, Rhizopus arrhizus, and by species of the genus Saksenaea spp
We present a case of rhino-orbital mucormycosis associated with ketoacidosis secondary to recentonset diabetes mellitus and infection with severe acquired respiratory syndrome coronavirus 2 (SARS COV2)
The COVID-19 pandemic precludes access to pathologies not related with this entity
Summary
Mucormycosis (Zygomycosis) is an invasive fungal infection, often acute and extremely severe caused by opportunist and ubiquitous fungi belonging to the class Phygomycetes, subclass Zygomycetes, order Mucorales, family Mucoraceae; usually by the following species: Absidia corymbifera, Apophysomyces elegans, Cunninghamella bertholletiae, Mucor rouxii, Rhizomucor pussillus, Rhizopus arrhizus, and by species of the genus Saksenaea spp. We present a case of rhino-orbital mucormycosis associated with ketoacidosis secondary to recentonset diabetes mellitus and infection with severe acquired respiratory syndrome coronavirus 2 (SARS COV2). A 24-year-old female, resident of Mexico City, with past medical history of obesity and being exposed to family members with COVID-19, presented to the ED of our tertiary care center with respiratory failure and oxygen saturation of 80%, given the findings she was managed in accordance with national and international guidelines Her family reported she began with pain in the left midface region six days prior, two days later she developed progressive left lid swelling and maxillary hypoesthesia; a primary care physician suspected infection, beginning treatment with oral antibiotics (amoxicillin-clavulanate 875/125 mg twicedaily) with partial remission of pain. Permission was granted by the patient family to reproduce the clinical photographs
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