Abstract
Introduction: This report discusses a rare case of antimuscle specific kinase (MuSK) positive myasthenia gravis (MG) during pregnancy, presenting with respiratory failure mimicking preeclampsia with severe features. Case Report: A 29-year-old primigravida presented to triage at 36 weeks with symptoms of dyspnea, orthopnea, and tachypnea necessitating cesarean delivery. Postpartum she developed neuromuscular respiratory failure leading to multiple re-intubations. Multi-system testing ultimately revealed anti-muscle specific kinase (anti-MuSK) positive serotype. Conclusion: Despite the challenges in diagnosis and management, interdisciplinary collaboration and long-term follow-up were emphasized. Teaching points highlight the need to consider autoimmune disorders in peripartum cardiopulmonary exacerbations. The case prompts further investigation into the physiologic implications of concurrent new-onset myasthenia gravis and preeclampsia.
Published Version
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