Abstract
BackgroundSolitary fibrous tumour of the uterine cervix is an extremely rare phenomenon. We present a case of the largest cervical tumour of this type in this anatomical location reported so far.Case presentationA 45-year old white female presented with abdominal pain, abnormal uterine bleedings and a 15 cm mass of the uterine cervix/left parametrium. Histological examination with immunohistochemistry of the tumour biopsy revealed diagnosis of solitary fibrous tumour. The patient underwent radical abdominal hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy. No recurrence has been observed for 8 months of follow-up.ConclusionsSolitary fibrous tumour can be occasionally found in patients with large cervical/parametrial masses. Immunohistochemistry was helpful in diagnosis and surgery was feasible and effective in treatment of our case of a large solitary fibrous tumour of the cervix.
Highlights
Solitary fibrous tumour of the uterine cervix is an extremely rare phenomenon
Solitary fibrous tumour can be occasionally found in patients with large cervical/parametrial masses
Immunohistochemistry was helpful in diagnosis and surgery was feasible and effective in treatment of our case of a large solitary fibrous tumour of the cervix
Summary
Our case and all the other three described SFTs of the cervix had benign histology (Table 1). The SFT described as a polyp in the cervical canal, accompanied stage FIGO Ib1 squamous cervical cancer [2]. There is no clearly defined morphologic and immunoreactivity criteria of SFT and the four described SFTs of the cervix differ somewhat in the immunoprofile (Table 1), immunohistochemical detection of CD34 and bcl-2 was helpful in our preoperational diagnosis of the large biopsy specimen, since the two markers were suggested to differentiate SFT from other spindle-cell tumours [3]. Surgery was feasible and has been effective so far in the very large cervical SFT we treated, as in the other two women with cervical SFTs for which follow-up data are available (Table 1). Follow-up is required since recurrences and malignant course were reported for these types of tumours in other anatomical locations [1]
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