Abstract
Pharmacology, the science of drug action, has helped to elucidate many basic physiological and pathological mechanisms in health and disease. Various animal experimental models have been designed to study the effect of drugs on living organisms and isolated tissues. These give an insight about where and how a drug acts, the mode of action of a drug, its effect on various body systems and probable adverse effects before administration of a drug. Therefore, the object of pharmacology is to provide such scientific data in animals as well as humans, which forms the basis of rational therapeutics.
 The Jalamahabhuta is fundamental base of origin for kapha dosha and mootra. These are supposed to have Asray-Asrayi Sambandha . It means these are directly proportional to each other. So by using the drug which is having the mootrala property Kapha may be controlled. Here an effort is made to prove this concept with modern parameters like immunomodulation, anti-inflammatory and antihistaminic activity.
Highlights
The role of research in ayurveda is to elucidate the principles of ayurveda and, to explain them in terms of modern parameters
An effort is made to substantiate the theory that Jala originates from kapha dosha and with the help of mootrala drug, it may be controlled because mootra and kapha are suppose to have Asray-Asrayi Sambandha (Ref.-Aashtang Hriday Sutra.11/26)
Jangala Deshastha Shitivaraka (Celosia argentea Linn.) DOSE CALCULATION FOR RAT [2] The suitable rat dose was calculated by referring the table of Paget and Barnes(1969)
Summary
The role of research in ayurveda is to elucidate the principles of ayurveda and, to explain them in terms of modern parameters. An effort is made to substantiate the theory that Jala originates from kapha dosha and with the help of mootrala drug, it may be controlled because mootra and kapha are suppose to have Asray-Asrayi Sambandha (Ref.-Aashtang Hriday Sutra.11/26). It means these are directly proportional to each other; increase in one factor is leads to increase in the other and decrease in one cause decrease in the other. By using the drug which is having the mootrala property Kapha may be controlled; because according to Ayurveda Kapha is the main causative factor for the disease Tamakashwasa.[1]. AIMS & OBJECTIVES (1).To asses the test drug for immunomodulation activity. (2) To evaluate the test drug for antiinflammatory activity. (3) To evaluate the test drug for antihistaminic activity
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