Abstract
Urologic disease states often result in intrinsic renal dysfunction. To provide comprehensive care to the patient, urologists must have a thorough understanding of renal physiology and pathophysiology. The aim of this chapter is to highlight the most clinically relevant aspects of these topics as they relate to urologic practice. We organize this broad topic in a clinically relevant fashion by separating renal function into three main categories: filtration and filtrate transport, hormonal regulation, and blood flow. Physiology and pathophysiology are presented together to encourage their understanding as multiple facets of one system, rather than as separate knowledge silos. Principles of physiology and pathophysiology in the kidney can direct therapeutic intervention on many levels for the practicing urologist.
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