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PDF Availablehttps://doi.org/10.1136/jitc-2022-sitc2022.0770
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Cite Journal: Journal for ImmunoTherapy of Cancer |  Publication Date: Nov 1, 2022 |
 Citations: 2 |
Affiliation: Texas Oncology, Carolina BioOncology Institute, Princess Margaret Cancer Centre, AbbVie (United States), Hospital Clínic de Barcelona, Indiana University – Purdue University Indianapolis, Institute of Cancer Research, James Cancer Hospital, Institut Claudius Regaud, Yale Cancer Center, Yale University, Sheba Medical Center
BackgroundGlycoprotein-A repetitions predominant (GARP) is expressed on regulatory T-cells and modulates release of active transforming growth factor β1 (TGFβ1), an immunosuppressive cytokine. ABBV-151 is a first-in-class monoclonal antibody (mAb) that...
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