761-1 Correlation of Residual Stenosis Immediately After Coronary Angloplasty with Long Term Prognosis

Abstract

Although low residual stenosis decreases Occurrence of restenosis within 3–6 months. its influence on long term prognosis remains unknown. Therefore, 595 consecutive patients with successful elective balloon coronary angioplasty (PTCA) for de novo lesions were divided into 3 groups according to the percent diameter stenosis (DS) immediately after PTCA. They were group A = DS < 15% (n = 129), group B = 15% ≤ DS ≤ 35% (n = 356), and group C = 35% < DS < 50% (n = 105). Background of each group was not statistically different in terms of age, history of myocardial infarction (MI), ejection fraction, distribution of both number of diseased vessels and target vessels and risk factors such as hypertension, hyperlipidemia and diabetes mellitus. End points of observation were 1) cardiac death (sudden death, fatal acute MI and death due to heart failure). 2) non cardiac death, and 3) cardiac event (acute MI and coronary bypass surgery). Kaplan-Meier survival analysis showed significant difference among 3 groups. Moreover, event free survival curve seems to be dependent on the residual stenosis (Figure). Multivariate analysis using Cox proportional hazard regression model identified that age, ejection fraction and residual stenosis were the independent determinants for the long term prognosis. Lower residual stenosis immediately after PTCA is beneficial not only for preventing early oCcurrence of restenosis but also for long term prognosis.