71. THE ASSOCIATION OF HIGHER SYSTOLIC BLOOD PRESSURE AT DISCHARGE AND DETERIORATION OF RENAL FUNCTION IN PATIENTS HOSPITALIZED FOR ACUTE DECOMPENSATED HEART FAILURE

Abstract

Introduction: Deterioration of renal function over time is associated with worse outcomes in patients with Acute Decompensated Heart Failure. Deterioration of renal function was the long-term consequences of RAAS system activation in ADHF. Higher systolic blood pressure was the most common precipitating factor for the acute heart failure event. Moreover, it was known that higher SBP was the predictor of renal function deterioration. Therefore, we hypothesized that the levels of SBP at discharge would have associations with post-discharge outcomes in hospitalized ADHF. Method: The study included 51 patients admitted to our hospital between November 2020 and January 2021 with ADHF event, patients were classified into high creatinine value and normal creatinine value based on creatinine at discharged. SBP at discharge was the primary outcome between two groups. Result: We examined changes in creatinine and grouped it into high creatinine value (creatinine level ≥1.5 mg/dl) and normal creatinine value (creatinine level <1.5 mg/dl). Overall, 60.8% (n = 31) of patients with AHDF were having higher creatinine value and 39.2% (n = 20) were having normal creatinine value. On Bivariate analysis, SBP at discharge was associated with higher creatinine value (p < 0.07) and result showed positive correlation between SBP at discharge and high creatinine value (r = 0.306, p = 0.31). Conclusion: In patients admitted for ADHF, higher creatinine value was correlated with higher SBP at discharge.