700 DIRECT EVIDENCE THAT VISCERAL FAT RATIO AFFECTS THE BASELINE ERECTILE FUNCTION AMONG THE RADICAL PROSTATECTOMY PATIENTS

Abstract

You have accessJournal of UrologySexual Function/Dysfunction/Andrology: Basic Research I1 Apr 2010700 DIRECT EVIDENCE THAT VISCERAL FAT RATIO AFFECTS THE BASELINE ERECTILE FUNCTION AMONG THE RADICAL PROSTATECTOMY PATIENTS Motoi Takeuchi, Shin-ichi Hisasue, Kohei Hashimoto, Ryoji Furuya, Akihiko Iwasawa, Keishi Ogura, Yu-ki Kyoda, Khoji Ichihara, Naoya Masumori, and Taiji Tsukamoto Motoi TakeuchiMotoi Takeuchi More articles by this author , Shin-ichi HisasueShin-ichi Hisasue More articles by this author , Kohei HashimotoKohei Hashimoto More articles by this author , Ryoji FuruyaRyoji Furuya More articles by this author , Akihiko IwasawaAkihiko Iwasawa More articles by this author , Keishi OguraKeishi Ogura More articles by this author , Yu-ki KyodaYu-ki Kyoda More articles by this author , Khoji IchiharaKhoji Ichihara More articles by this author , Naoya MasumoriNaoya Masumori More articles by this author , and Taiji TsukamotoTaiji Tsukamoto More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2010.02.1141AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Metabolic syndrome is a cluster of cardio-metabolic risk factors including visceral fat accumulation, dyslipidemia, hyperglycemia and hypertension. It is also associated with erectile dysfunction in aged male. We investigated the impact of visceral fat measured with the computed tomography (CT) on the baseline erectile function in the radical prostatectomy patients. METHODS We reviewed 74 of 178 organ confined prostate cancer patients who underwent radical prostatectomy between 2005 and 2009 in our institution. The patients whose preoperative CT was available were included, and those who had any kind of testosterone ablation were excluded. We measured both area of the visceral fat and the subcutaneous fat at the level of the umbilicus from abdominal CT and calculated the visceral fat ratio. Erectile function was assessed by IIEF5 and maximum penile circumferential change (MPCC) during a night. RESULTS Median age was 66 years and median visceral fat ratio was 51.8% (range 20.3-72.4). Median IIEF5 score was 15 and median MPCC was 2.6cm (range 0.4-5.0). We investigated the relationship between the visceral fat ratio and erectile function, and there was no significant difference in the IIEF5 score, but 75‰ of MPCC (3.25cm) showed the significant difference in the univariate analysis. We carried out the multivariate analysis using parameters which were selected as risk factors for erectile dysfunction including age, smoking, hypertension, diabetes, BMI and visceral fat ratio. It revealed that a single predictor for the baseline erectile function was visceral fat ratio (p=0.04). The median visceral fat ratio was significantly higher in the MPCC < 3.25cm group (52.4%) than ≥ 3.25cm group (49.9%). (p=0.04, Fig. 1) CONCLUSIONS This is the first study which suggested the impact of the visceral fat accumulation on the erectile function. The further study will be necessary to clarify the influence of the visceral fat ratio on the recovery of erectile function following the radical prostatectomy. Sapporo, Japan© 2010 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 183Issue 4SApril 2010Page: e273 Advertisement Copyright & Permissions© 2010 by American Urological Association Education and Research, Inc.MetricsAuthor Information Motoi Takeuchi More articles by this author Shin-ichi Hisasue More articles by this author Kohei Hashimoto More articles by this author Ryoji Furuya More articles by this author Akihiko Iwasawa More articles by this author Keishi Ogura More articles by this author Yu-ki Kyoda More articles by this author Khoji Ichihara More articles by this author Naoya Masumori More articles by this author Taiji Tsukamoto More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...