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Abstract
5-Hydroxymethylcytosines (5hmCs) are stable epigenetic marks in the regions of active gene expression and regulation that underlie development and tumorigenesis. To investigate 5hmC patterns in tumor tissues, we characterized a collection of 267 fresh frozen tumor and non-tumor tissue samples using Bluestar Genomics’ genome-wide 5hmC profiling technology. The tumor samples represent five tissue types at various stages of cancer: breast, colon, lung, ovary, and pancreas.
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