Abstract
In this study, microcalorimetric measurements were carried out on 44 tumorous and non-tumorous tissue samples from organs of the uro-genital tract as well as from the mammae and the colon. The aim of this investigation was to compare the results of the microcalorimetric measurements with those of impulse-cytophotometrical and histological examinations in order to provide evidence of the metabolic activity of tumorous and non-tumorous tissues. The course of the heat output of the tissue samples was measured at one-minute intervals and graphically displayed as a function of time. For the evaluation of the results of the microcalorimetrically measured values, the maxima ( P max), the mean values P, and the contour integrals W of the microcalorimetric curves were determined. It was found that, without exception, all measured metabolic activity values of tumorous tissue samples were distinctly higher than those of non-tumorous tissue samples from the same organ. We conclude that through a microcalorimetric analysis, it is possible to differentiate between healthy and tumorous tissue samples on the basis of a varyingly higher metabolic activity of the malignant samples.
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