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PDF Availablehttps://doi.org/10.1136/jitc-2023-sitc2023.0611
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Cite Journal: Journal for ImmunoTherapy of Cancer |  Publication Date: Nov 1, 2023 |
 Citations: 1 |  License type: CC BY-NC 4.0 |
Affiliation: USC Norris Cancer Hospital, University of Iowa Hospitals and Clinics, Xilio Therapeutics (United States), Massachusetts General Hospital, Carolina BioOncology Institute, Rutgers, The State University of New Jersey, The Ohio State University, HealthPartners, Regions Hospital, Sarah Cannon, University of California, Los Angeles, MedStar Georgetown University Hospital, Georgetown University
BackgroundAldesleukin requires high systemic doses (8.4 million IU/kg equaling 0.518 mg/kg per weekly cycle) to achieve therapeutic benefit; however, such doses typically result in life-threatening toxicities. ‘Non-α’ interleukin-2 (IL-2) agents...
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