Abstract
Introduction The etiology of pre-eclampsia (PE) is not yet fully understood, though current literature indicates an upregulation of inflammatory mediators produced by the placenta as a potential causal mechanism. Vitamin D is known to have anti-inflammatory properties and there is evidence of an inverse relationship between dietary calcium intake and the incidence of PE. Methods We studied 150 patients attended by the Obstetrics Department of the Barbacena Medical School and the Federal University of Juiz de Fora. All patients underwent vitamin D dosing in the first, second and third trimesters of pregnancy. The cutoff point was 30 mcg/dl and out of pregnancy 20 ng/ml. Results The median vitamin D level in pregnant women was considered low ( 0.05). Conclusions The authors report the importance of maintaining normal levels of vitamin D in pregnant women, considering the formation of the fetus, but there was no association between vitamin D and preeclampsia in this study.
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