Abstract
The design of artificial extracellular matrix (ECM) is very important in tissue engineering and regenerative medicine because the artificial ECM controls cellular behaviors, such as adhesion, proliferation, migration, survival, and differentiation. Especially, three-dimensional (3D) ECMs have several functions, such as provision of cell-adhesive substrate, regulation of 3D tissue structure, and presentation of cell-adhesion signals, mechanical signals, and growth factors. This chapter covers mechanism of specific interaction between galactose moieties in the artificial ECMs and asialoglycoprotein receptors on the hepatocytes. Besides, we explain the recent developments on liver tissue engineering using marine biomaterials, such as chitosan, alginate, and pullulan among naturally derived polymers.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
