Abstract
Platelets form thrombi that occlude arteries; however, the molecular mechanisms regulating platelet thrombus formation are poorly understood. One of the most important platelet inhibitory signalling systems is mediated by nitric oxide (NO). Within platelets, NO is synthesized by endothelial nitric oxide synthase (eNOS); however, recent studies have questioned the presence of eNOS in platelets. Due to this discrepancy in detecting platelet eNOS, we hypothesized that two platelet subpopulations exist based on the presence and absence of eNOS; and if so, that these two subpopulations may have differential roles in hemostatic/thrombotic reactions.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
