51 Vitamin D deficiency shows no relationship to disease activity in an irish inflammatory bowel disease (IBD) population

Abstract

Background Low levels of vitamin D have been widely reported in IBD with evidence suggesting a role in disease severity and treatment. Aim Ireland has high rates of vitamin D deficiency both in IBD and general populations. Studies investigating correlation of vitamin D deficiency and disease parameters have been mixed. Method We conducted a single centre retrospective study in our hospital from Jan 2015- June 2016. The aim was to assess the prevalence of vitamin D deficiency in IBD and non-IBD cohorts and to assess the impact of vitamin D deficiency on disease activity in IBD. Patients were separated into 4 groups: Crohns Disease (CD), Ulcerative Colitis (UC), general gastroenterology (GI) and general medical (non-GI). Basic demographic data disease specific information was recorded. Vitamin D deficiency was defined as Results 395 patients were studied: 157 CD, 70 UC, 75 GI and 93 non-GI. IBD patients were found to have high rates of Vitamin D deficiency (33% levels Conclusions We found very high rates of vitamin D deficiency in both IBD and non-IBD patients. Absolute levels did not differ significantly between groups. This may be accounted for by high overall prevalence of Vitamin D deficiency in this population or by confounders in the control population.