Abstract
Indirect calorimetry is the measurement of oxygen absorption by a subject through respiration, creating heat production in the body. Heat production divided by the absolute temperature is the entropy production within the body; thus entropy production is more easily obtained than by direct calorimetry. From the entropy productions at various ages of the human life cycle, the age dependence of human entropy production is obtained for men and women. Entropy production in an individual (and also per unit body surface) manifests two phases over the human life span: an initial increasing stage and a later decreasing stage until 75 years of age. A rather arbitrary extrapolation beyond this age to 120 years shows that entropy production in an individual at the fertilized egg stage is at about the same level as at 120 years. The trends of entropy production in humans are a rapid increase in an initial short period of development and then the slow decrease over the later long period of aging. This is proposed as a general Principle of Organization applicable to complex biotic systems in general.
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