Abstract
The role of bioactive dressings derived from natural resources in managing both acute and chronic wounds is discussed. Bioactive dressings deliver substances active in wound healing either by delivery of bioactive compounds or by being constructed from materials having endogenous activity. These materials include hydrocolloids, hydrogels, alginates, collagens, honey dressings, chitosan, chitin, derivatives from chitosan or chitin and biotextiles. The application of dibutyrylchitin (DBC) derived from chitin is extensively reviewed. The O-butyrylation of chitin or chitosan is an important modification of chitin which increases the biochemical activity of chitin or chitosan. Future developments in bioactive wound dressing materials based on chitin, chitosan and their derivatives are indicated using the increased knowledge and understanding of the action of these dressings in wound healing.
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