Abstract

:Objective To explore thepossibility of united test of CA72-4, CA19-9 in gastric juice in diagnosis of gastriccarcinoma.Methods The gastric juices were respectively obtained by liquid collector madeby ourselves through gastreecope in study group(30 cases of gastric cancer) and controlgroups(32 cases of gastratrophia,30 cases of gastric ulcer,and 30 cases of chronicsuperficial gastritis).The gastric juice content of CA72-4, CA19-9 were determinedsynchronously with ES-300 auto-enzymoimmuno-analyzer.Results The gastric juice contents ofCA72-4,CA19-9 were (83.54±143.70) U/ml and (47.05±29.64) U/ml, and the positive rateswere 76.66% and 43.33% in study group,respectively,and all higher than those of controlgroups(P <0.01 ).The level of CA72-4 was high in two of 32 patients withgastratrophia,and one was diagnosed as gastric carcinoma after nine monthsfollow-up.Conclusion The combined detection of CA72-4 and CA19-9 provide main evidence forthe diagnosis of gastric cancer and diagnostric significance of advanced gastric cancer.

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