Abstract
Aspirin is an antiplatelet drug that works by inhibiting the enzyme cyclooxygenase, thus preventing in vitro platelet aggregation in response to arachidonic acid. The most common use of aspirin is for prophylaxis of arterial thrombosis. However, several published studies in the neurology and cardiology literature suggest that from 5.5% to 60% of patients appear to be resistant to the antiplatelet effects of aspirin. These data were often generated using laboratory assays other than whole blood aggregometry …
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